Jacob and Monod described an operon as a simple control circuit where a collection of structural genes could be regulated in a coordinated fashion. These structural genes code for a group of proteins that are responsible for a particular metabolic function.
Jacob, Monod, the Lac Operon, and the PaJaMa …
Building on experiments for demonstrating that lambda phage genes can be both induced and repressed in bacteria, the investigators established that changes in need for lactose utilization lead to negative …
Jacob and Monod: From Operons to EvoDevo
So in what became known as the PaJaMa experiment, Pardee, Jacob and Monod set out to test whether inducibility or constitutive expression was dominant. To do this, they mated a lacZ + lacI + male with a lacZ – lacI – …
The 50th Anniversary of the Publication of the Operon Theory in …
Inspired by the discovery of allosteric transitions in proteins as a mechanism for control of protein activity by Monod, Changeux and Jacob, 12 the model was further refined to …
Quantitative approaches to the study of bistability in the lac …
According to the construction of Jacob & Monod, an operon consists of a set of structural genes that are regulated together, ... (1959) proposed a more subtle interpretation of their …
Genetic Regulatory Mechanisms in the Synthesis of Proteins
Jacob and Monod along with Pardee studied various mutations in order to determine how regulation of the operon works. This experiment was called the PAJAMO experiment, named …
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Jacob and Monod described an operon as a simple control circuit where a collection of structural genes could be regulated in a coordinated fashion. These structural genes code for a group of proteins that are responsible for a particular metabolic function.
Building on experiments for demonstrating that lambda phage genes can be both induced and repressed in bacteria, the investigators established that changes in need for lactose utilization lead to negative …
So in what became known as the PaJaMa experiment, Pardee, Jacob and Monod set out to test whether inducibility or constitutive expression was dominant. To do this, they mated a lacZ + lacI + male with a lacZ – lacI – …
Inspired by the discovery of allosteric transitions in proteins as a mechanism for control of protein activity by Monod, Changeux and Jacob, 12 the model was further refined to …
According to the construction of Jacob & Monod, an operon consists of a set of structural genes that are regulated together, ... (1959) proposed a more subtle interpretation of their …
Jacob and Monod along with Pardee studied various mutations in order to determine how regulation of the operon works. This experiment was called the PAJAMO experiment, named …